No, but it sure has had some strange ingredients over the years.
The earliest known reference to a toothpaste is in a manuscript from Egypt in the 4th century A.D., which prescribes a mixture of powdered salt, pepper, mint leaves, and iris flowers. The Romans used toothpaste formulations based on human urine. Since urine contains ammonia, it was probably effective in whitening teeth. An 18th century American toothpaste recipe containing burnt bread has been found. Another formula around this time called for dragon's blood, cinnamon, and burnt alum.
However, toothpastes or powders did not come into general use until the 19th century. In the early 1800s, the toothbrush was usually used only with water, but tooth powders soon gained popularity. Most were home made, with chalk, pulverized brick, and salt being common ingredients. An 1866 Home Encyclopedia recommended pulverized charcoal, and cautioned that many patented tooth powders then commercially marketed did more harm than good.
https://en.wikipedia.org/wiki/Toothpaste
