Of interest: "This Brief Tragedy: Unraveling the Todd-Dickinson Affair," by John Evangelist Walsh.
Mr. Walsh believes the circumstances surrounding her death were suspicious. After having breakfast with her family on May 13, 1886, she was alone in her room when she fainted. She fell into a coma that lasted 60 hours, experiencing convulsions and labored breathing. Mr. Walsh states that the latter symptom is "not necessarily" consistent with death by kidney failure, indicating that she died for some reason other than her illness. He suggests that she may have taken an overdose of a prescription drug containing strychnine.
Sans autopsy/blood work/etc., we will probably never know.