The County isn't called Lancastershire because its name is Aroostook.
Aroostook County (known as the County) is a county located in the U.S. state of Maine. In 2000, its population was 73,938. It is the largest county in the state. Its seat is Houlton. In land area, Aroostook County is the largest U.S. county east of the Mississippi River. Among residents of Maine, it is often referred to simply as "the County."
https://en.wikipedia.org/wiki/Aroostook_County,_Maine
Aroostook was named for its most prominent river, and is derived from a native Wabanaki word, sometimes spelled Restook, Ristook, Aroostic, and finally, Aroostook.
Different people have assigned different meanings to the name in the original language. Moses Greenleaf supposed that it is the same name as Wal-loos-took, the Wabanaki name for the St. John, which he understood to mean good river or fine river. On the original tracing of the map that he drew of Maine, drawn about 1814, it was spelled in the way that it is now spelled -- Aroostook.
Sockabasin, a Penobscot Indian, told William Willis in 1840 that the name meant smooth river. In his Woods and Lakes of Maine, L. L. Hubbard writes: "Aroostook, Alloostook, Oolastook, 'beautiful river'," and refers to Rand's Micmac Reader. Wallastook, or Woolastook, he says, means "stream where you get smooth boughs." He concludes that authorities generally think that the word means fine, good or beautiful river.
http://kenanderson.net/aroostook/war.html